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If fact, brain scan studies teach us that just one puff and up to 50% of dopamine pathway receptors become occupied by nicotine

"Our results demonstrate that overall electronic cigarettes seem to be less harmful than regular cigarettes, but their elevated content of toxic metals such as nickel and chromium do raise concerns," said study author Constantinos Sioutas, a professor at the USC Viterbi School of Engineering

In reality, there could be unmeasured confounding differences between smokers and non-smokers, for example, differences in socio-economic status, diet, or other health behaviours, that also influence life expectancy

Reproductive system Tobacco can have detrimental effects on sperm production, including reduced concentrations of sperm in the semen and reduced concentrations of normal and motile sperm

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